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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAMK2B
All Species:
13.64
Human Site:
T254
Identified Species:
33.33
UniProt:
Q13554
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13554
NP_001211.3
664
72727
T254
N
L
I
N
Q
M
L
T
I
N
P
A
K
R
I
Chimpanzee
Pan troglodytes
XP_001164798
668
73778
T254
D
L
I
N
K
M
L
T
I
N
P
S
K
R
I
Rhesus Macaque
Macaca mulatta
XP_001095396
1012
110008
T600
N
L
I
N
Q
M
L
T
I
N
P
A
K
R
I
Dog
Lupus familis
XP_863379
683
75683
T254
N
L
I
N
Q
M
L
T
I
N
P
A
K
R
I
Cat
Felis silvestris
Mouse
Mus musculus
P28652
542
60442
C148
N
L
L
L
A
S
K
C
K
G
A
A
V
K
L
Rat
Rattus norvegicus
P08413
542
60383
C148
N
L
L
L
A
S
K
C
K
G
A
A
V
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZKI0
479
54184
F85
D
S
I
S
E
E
G
F
H
Y
L
V
F
D
L
Frog
Xenopus laevis
Q9DG02
475
53914
E81
R
L
H
D
S
I
S
E
E
G
F
H
Y
L
V
Zebra Danio
Brachydanio rerio
Q6DGS3
554
62366
A160
K
L
A
D
F
G
L
A
I
E
V
Q
G
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q00168
530
59901
D136
Q
N
G
V
V
H
R
D
L
K
P
E
N
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
66.7
62.6
74.5
N.A.
81
80.8
N.A.
N.A.
64
63.4
69.8
N.A.
60
N.A.
N.A.
N.A.
Protein Similarity:
100
77.2
63.4
81.9
N.A.
81.3
81.1
N.A.
N.A.
68.8
68
76.1
N.A.
68
N.A.
N.A.
N.A.
P-Site Identity:
100
80
100
100
N.A.
20
20
N.A.
N.A.
6.6
6.6
20
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
40
40
N.A.
N.A.
33.3
26.6
26.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
20
0
0
10
0
0
20
50
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% C
% Asp:
20
0
0
20
0
0
0
10
0
0
0
0
0
20
0
% D
% Glu:
0
0
0
0
10
10
0
10
10
10
0
10
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
10
0
0
10
0
10
0
0
% F
% Gly:
0
0
10
0
0
10
10
0
0
30
0
0
10
0
0
% G
% His:
0
0
10
0
0
10
0
0
10
0
0
10
0
0
0
% H
% Ile:
0
0
50
0
0
10
0
0
50
0
0
0
0
0
40
% I
% Lys:
10
0
0
0
10
0
20
0
20
10
0
0
40
20
0
% K
% Leu:
0
80
20
20
0
0
50
0
10
0
10
0
0
20
40
% L
% Met:
0
0
0
0
0
40
0
0
0
0
0
0
0
0
0
% M
% Asn:
50
10
0
40
0
0
0
0
0
40
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% P
% Gln:
10
0
0
0
30
0
0
0
0
0
0
10
0
0
10
% Q
% Arg:
10
0
0
0
0
0
10
0
0
0
0
0
0
40
0
% R
% Ser:
0
10
0
10
10
20
10
0
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
40
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
10
0
0
0
0
0
10
10
20
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _